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Accueil du site > Actualités > increased oxidation of iron, RNA and dystrophic microglia in the brains of older male marmosets.

increased oxidation of iron, RNA and dystrophic microglia in the brains of older male marmosets.

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The editorial team of the American Journal of Primatology has chosen to highlight the following article : Loss of ferritin-positive microglia relates to increased iron, RNA oxidation, and dystrophic microglia in the brains of aged male marmosets Juan de Dios Rodríguez-Callejas, Daniel Cuervo-Zanatta, Abraham Rosas-Arellano, Caroline Fonta, Eberhard Fuchs, Claudia Perez-Cruz Volume 81, Issue 2, February 2019->https://onlinelibrary.wiley.com/doi...] This paper, which involves a CERCO researcher, presents how ferritin provides microglia protection in adult and elderly marmosets, while in elderly subjects, the decline in ferritin and the increased amount of iron in brain tissue may be related to the increase in the number of cells with oxidized RNA, possibly associated with the development of neurodegeneration...

Mise à jour 09/04/2019